Responsibilities
Research Group Leader
Contact
Molecular Physiology of Neurogenesis
and
Max Planck Institute of Psychiatry
Developmental Neurobiology
Email:
silvia_cappello@psych.mpg.de
Website:
https://www.en.bmc.med.uni-muenchen.de/research/research_areas/principal_investigators/cappellos/index.html
Website:
http://www.psych.mpg.de/2049085/cappello
Further Information
Research Focus: Neurogenesis and Neuronal Migration
Key words: Neural stem cells, neuronal migration, cortical malformations, cytoskeleton
Graduated GSN student: Dr. Isabel Buchsbaum
Selected publications:
• Johannes Klaus*, Sabina Kanton*, Christina Kyrousi*, Ane C. Ayo-Martin, Rossella Di Giaimo, Stephan Riesenberg, Adam C. O’Neill, J. Gray Camp, Chiara Tocco, Malgorzata Santel, Ejona Rusha, Micha Drukker, Mariana Schroeder, Magdalena Götz, Stephen P. Robertson, Barbara Treutlein# and Silvia Cappello#. Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia. Nature Medicine 2019, 25(4):561-568 - *equally contributing authors, #corresponding authors
• Isabel Y. Buchsbaum & Silvia Cappello. Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models. Development 2019, 146:dev163766.
• Adam C. O’Neill, Christina Kyrousi, Johannes Klaus, Richard J. Leventer, Edwin P. Kirk, Andrew Fry, Daniela T. Pilz, Tim Morgan, Zandra A. Jenkins, Micha Drukker, Samuel F. Berkovic, Ingrid E. Scheffer, Renzo Guerrini, David M. Markie, Magdalena Götz, Silvia Cappello#$ and Stephen P. Robertson#$. A primate-specific isoform of PLEKHG6 regulates neurogenesis and neuronal migration. Cell Reports 2018, 25,2729-2741 - #corresponding authors, $equally contributing authors
• Adam C. O’Neill, Christina Kyrousi, Melanie Einsiedler, Ingo Burtscher, Micha Drukker, David M. Markie, Edwin P. Kirk, Magdalena Götz, Stephen P. Robertson and Silvia Cappello. Mob2 insufficiency disrupts neuronal migration in the developing cortex. Frontiers in Cellular Neuroscience 2018, 12:57
• Silvia Cappello, Mary J. Gray, Caroline Badouel, Simona Lange, Melanie Einsiedler, Myriam Srour, David Chitayat, Fadi F. Hamdan, Zandra A. Jenkins, Tim Morgan, Nadia Preitner, Tami Uster, Jackie Thomas, Patrick Shannon, Victoria Morrison, Nataliya Di Donato, Lionel Van Maldergem, Teresa Neuhann, Ruth Newbury-Ecob, Marielle Swinkells, Paulien Terhal, Louise C. Wilson, Petra J.G. Zwijnenburg, Andrew J. Sutherland-Smith, Michael A. Black, David Markie, Jacques L. Michaud, Michael A. Simpson, Sahar Mansour, Helen McNeill, Magdalena Götz and Stephen P. Robertson. Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nature Genetics 2013, 45(11):1300-1308 - highlighted by Faculty of 1000
• Silvia Cappello*, Christian R.J. Böhringer*, Matteo Bergami, Karl-Klaus Conzelmann, Alexander Ghanem, Giulio Srubek Tomassy, Paola Arlotta, Marco Mainardi, Matteo Caleo, Jolanda van Hengel, Cord Brakebusch and Magdalena Götz. A radial glia specific role of RhoA in double-cortex formation. Neuron 2012, 73(5):911-924 - *equally contributing authors