Responsibilities
Director "Research Unit Protein Science"
Contact
Deutsches Forschungszentrum für
Gesundheit und Umwelt GmbH
Research Unit Protein Science
Heidemannstr. 1
D-80939 München
Phone:
+49 (0)89 / 3187-3941
Fax:
+49 (0)89 / 3187-4426
Email:
hauck@helmholtz-muenchen.de
Website:
http://www.helmholtz-muenchen.de/en/proteinscience/institute/about-us/staff/mitarbeiter/ma/2129/index.html
Further Information
Research focus: Proteome-wide identification of disease mechanisms and neurodegenerative processes in retina and brain. Functional characterization of retinal Müller glial cells in health and disease.
Key words: Proteomics, LC-MSMS mass spectrometry, posttranslational modifications, Müller glial cells, retinal degeneration, diabetic retinopathy, age-related macular degeneration, functional DNA-protein complexes, cis-regulatory SNPs.
Selected publications:
von Toerne C, Laimighofer M, Achenbach P, Beyerlein A, de las Heras Gala T, Krumsiek J, Theis FJ, Ziegler AG, Hauck SM. (2017 ) Peptide serum markers in islet autoantibody-positive children. Diabetologia. 60(2):287-295
Palfi A, Hokamp K, Hauck SM, Vencken S, Millington-Ward S, Chadderton N, Carrigan M, Kortvely E, Greene CM, Kenna PF, Farrar GJ. (2016) microRNA regulatory circuits in a mouse model of inherited retinal degeneration. Sci Rep. 6:31431.
Yang J, Bassuk AG, Merl-Pham J, Hsu C-W, Colgan D, Li X, Au KS, Zhang L, Smemo S, Nagahama Y, Grossbach A, Howard M, Kawasaki H, Feldstein N, Dobyns W, Northrup H, Hauck SM, Ueffing M, Mahajan V, Tsang SH.( 2016) Catenin delta-1 (CTNND1) phosphorylation controls the mesenchymal to epithelial transition in astrocytic tumors. Hum Mol Genet. 25(19):4201-4210
von Toerne C, Huth C, de las Heras Gala T, Kronenberg F, Herder C, Koenig W, Meisinger C, Rathmann W, Waldenberger W, Roden M, Peters A, Thorand B and Hauck SM. (2016) MASP1, THBS1, GPLD1, APOA4 - novel biomarkers associated with prediabetes: the KORA F4 study. Diabetologia. 59(9):1882-92.
Nestor CE, Lentini A, Hägg Nilsson C, Gawel D, Gustafsson M, Mattson L, Wang H, Rundquist O, Meehan RR, Klocke B, Seifert M, Hauck SM, Laumen H, Zhang H, Benson M. (2016) 5-hydroxymethylcytosine remodeling precedes lineage specification during differentiation of human CD4+ T-cells. Cell Rep. 16(2):559-70.
Deeg CA, Amann B, Lutz K, Hirmer S, Lutterberg K, Kremmer E, Hauck SM. (2016) Aquaporin 11, a regulator of water efflux at retinal Müller glial cell surface decreases concomitant with immune mediated gliosis. J Neuroinflammation. 13(1):89.