Graduate School of Systemic Neurosciences GSN-LMU
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Antje Grosche

Prof. Dr. Antje Grosche

GSN associate faculty

Responsibilities

Research Group Leader "Molecular Neurophysiology"

Contact

Ludwig-Maximilians-Universität München
Department of Physiological Genomics
BioMedical Center - BMC
Großhaderner Str. 9
D-82152 Planegg-Martinsried

Phone: +49 (0)89 / 2180-75527
Fax: +49 (0)89 / 2180-75216

Further Information

Research focus: Understanding the role of glial functions in the healthy and diseased retina implementing mouse models of multifactorial (e.g. diabetic retinopathy) or inherited retinal degeneration

Selected publications:

Slezak M*, Grosche A*, Niemiec A*, Tanimoto N, Pannicke T, Münch TA, Crocker B, Isope P, Härtig W, Beck SC, Huber G, Ferracci G, Perraut M, Reber M, Miehe M, Demais V, Lévêque C, Metzger D, Szklarczyk K, Przewlocki R, Seeliger M, Sage-Ciocca D, Hirrlinger J, Reichenbach A, Reibel S, Pfrieger FW. 2012. Relevance of exocytotic glutamate release from retinal glia. Neuron, 74:405-416. *Equally contributing first authors PMID: 22578502

Grosche A, Reichenbach A. 2013. Neuroscience. Developmental refining of neuroglial signaling? Science, 339:152-153. PMID: 23307730

Pannicke T, Frommherz I, Biedermann B, Wagner L, Sauer K, Ulbricht E, Härtig W, Krügel U, Ueberham U, Arendt T, Illes P, Bringmann A, Reichenbach A, Grosche A. 2014. Differential effects of P2Y1 deletion on glial activation and survival of photoreceptors and amacrine cells in the ischemic mouse retina. Cell Death Dis, 5:e1353. PMID: 25077539

Grosche A, Hauser A, Lepper MF, Mayo R, von Toerne C, Merl-Pham J, Hauck SM. 2016. The proteome of native adult Muller glial cells from murine retina. Mol Cell Proteomics, 15:462-480. PMID: 26324419

Wagner L, Pannicke T, Rupprecht V, Frommherz I, Volz C, Illes P, Hirrlinger J, Jägle H, Egger V, Haydon PG, Pfrieger FW, Grosche A. 2017. Suppression of SNARE-dependent exocytosis in retinal glial cells and its effect on ischemia-induced neurodegeneration. Glia, 65:1059-1071. PMID: 28370368