Graduate School of Systemic Neurosciences GSN-LMU
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Silvia Cappello

Dr. Silvia Cappello

GSN associate faculty

Responsibilities

Research Group Leader

Contact

Max Planck Institute of Psychiatry
Kraepelinstr. 2, D-80804 Munich

Phone: +49 (0)89 / 3062-2253

Website: http://www.psych.mpg.de/2049085/cappello

Further Information

Research Focus: Neurogenesis and Neuronal Migration

Key words: Neural stem cells, neuronal migration, cortical malformations, cytoskeleton

Current GSN student: Isabel Buchsbaum

Selected publications:

Marie-Theres Schmid, Franziska Weinandy, Silvia Cappello and Magdalena Götz. The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration. Frontiers in Neuroscience 2014, 8:215

Silvia Cappello, Mary J. Gray, Caroline Badouel, Simona Lange, Melanie Einsiedler, Myriam Srour, David Chitayat, Fadi F. Hamdan, Zandra A. Jenkins, Tim Morgan, Nadia Preitner, Tami Uster, Jackie Thomas, Patrick Shannon, Victoria Morrison, Nataliya Di Donato, Lionel Van Maldergem, Teresa Neuhann, Ruth Newbury-Ecob, Marielle Swinkells, Paulien Terhal, Louise C. Wilson, Petra J.G. Zwijnenburg, Andrew J. Sutherland-Smith, Michael A. Black, David Markie, Jacques L. Michaud, Michael A. Simpson, Sahar Mansour, Helen McNeill, Magdalena Götz and Stephen P. Robertson. Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt mammalian neuroprogenitor cell proliferation, differentiation and cerebral cortical development. Nature Genetics 2013, 45(11):1300-1308

Ronny Stahl, Tessa Walcher, Camino De Juan Romero, Gregor A. Pilz, Silvia Cappello, Martin Irmler, José Miguel Sanz Anquela, Johannes Beckers, Robert Blum, Victor Borrell and Magdalena Götz. Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate. Cell 2013, 153(3):535-549

Silvia Cappello. Small Rho-GTPases and cortical malformations: fine-tuning the cytoskeleton stability. Small GTPases 2013, 4(1):51-56

Silvia Cappello*, Christian R.J. Böhringer*, Matteo Bergami, Karl-Klaus Conzelmann, Alexander Ghanem, Giulio Srubek Tomassy, Paola Arlotta, Marco Mainardi, Matteo Caleo, Jolanda van Hengel, Cord Brakebusch and Magdalena Götz. A radial glia specific role of RhoA in double-cortex formation. Neuron 2012, 73(5):911-924

Silvia Cappello*, Pascale Monzo* and Richard B. Vallee. NudC is required for interkinetic nuclear migration and neuronal migration during cortical development. Developmental Biology 2011, 357(2):326-35

Silvia Cappello, Alessio Attardo, Xunwei Wu, Takuji Iwasato, Shigeyoshi Itohara, Michaela Wilsch-Bräuninger, Hanna M Eilken, Michael A Rieger, Timm T Schroeder, Wieland B Huttner, Cord Brakebusch and Magdalena Götz. The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nature Neuroscience 2006, 9(9):1099-1117