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Neural stem cells

The flow of cerebrospinal fluid is a key signal for neural stem cell renewal

25.05.2018

A team of researchers headed by MCN/GSN Member Prof. Magdalena Götz and their collaborators from the LMU Chair of Neurobiology, lead by Prof. Benedikt Grothe, and the Henrich-Heine University Düsseldorf have discovered that the flow of cerebrospinal fluid is a key signal for neural stem cell renewal.

“Neural stem cells in the brain can divide and mature into neurons and this process plays important roles in various regions of the brain – including olfactory sense and memory,” explains Magdalena Götz, Head of LMU Department of Physiological Genomics and Director of the Institute for Stem Cell Research at Helmholtz Zentrum München. “These cells are located in what is known as the neurogenic stem cell niche one of which is located at the walls of the lateral ventricles*, where they are in contact with circulating cerebrospinal fluid.”

Source: LMU News