Responsibilities
Lab Head Research Unit Therapy Development, University Clinic
Contact
Institute of Clinical Neuroimmunology
Ludwig-Maximilians-Universität München
Großhaderner Strasse 9
82152 Planegg-Martinsried
Phone:
+49 (089) 2180 71663
Fax:
+49 (0)89 / 2180-71811
Email:
Florence.Bareyre@med.uni-muenchen.de
Website:
http://www.klinikum.uni-muenchen.de/Institut-fuer-Klinische-Neuroimmunologie/en/forschung/index.html
Further Information
Research focus: Mechanisms of axon damage and limited axonal repair, development of novel therapeutic strategies to protect axons against damage and/or improve axonal repair
Key words: Multi-photon imaging, high-resolution confocal microscopy, viral and transgenic labelling, real-time cellular and molecular interactions, tissue damage and repair, in vivo pathogenesis, genetic and pharmacological manipulations, new therapeutic strategies, axonal protection and repair
GSN students
- Current: Carmen Katharina Denecke, Charlene Granier, Almir Aljovic
- Graduated: Dr. Kristina Loy, Dr. Laura Empl
Selected publications:
Jacobi A, Loy K, Schmalz AM, Hellsten M, Umemori H, Kerschensteiner M, Bareyre FM. FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord. EMBO J. 2015 May 5;34(9):1231-43. doi: 10.15252/embj.201490578.
Lang C, Bradley PM, Jacobi A, Kerschensteiner M, Bareyre FM. STAT3 promotes corticospinal remodelling and functional recovery after spinal cord injury. EMBO Rep. 2013 Oct;14(10):931-7. doi: 10.1038/embor.2013.117.
Bareyre FM, Garzorz N, Lang C, Misgeld T, Büning H, Kerschensteiner M. In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6282-7. doi: 10.1073/pnas.1015239108.
Misgeld T, Kerschensteiner M, Bareyre FM, Burgess RW, Lichtman JW. Imaging axonal transport of mitochondria in vivo. Nat Methods. 2007 Jul;4(7):559-61.
Bareyre FM, Kerschensteiner M, Misgeld T, Sanes JR. Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury. Nat Med. 2005 Dec;11(12):1355-60.
Bareyre FM, Kerschensteiner M, Raineteau O, Mettenleiter TC, Weinmann O, Schwab ME. The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat Neurosci. 2004 Mar;7(3):269-77.