Responsibilities
Chair of the Division of Neurobiology
Contact
Division Neurobiology
Großhaderner Straße 2
D-82152 Planegg-Martinsried
Room:
B03.002
Phone:
+49 (0)89 / 2180-74302
Fax:
+49 (0)89 / 2180-74304
Email:
neuro@bio.lmu.de
Website:
http://neuro.bio.lmu.de/research_groups/res-grothe_b/index.html
Website:
http://neuro.bio.lmu.de/members/systems_neuro_grothe/grothe_b/index.html
Further Information
Research focus: Structure, physiology, and function of neuronal circuits processing spatio-temporal information, their evolution and development. Research topics span from ion-channels and biophysics (in vitro physiology) via circuit structure and function (synaptic function, myelination patterns etc.), to in vivo single cell and populations responses, population coding (modelling), psychoacoustics and perception. Methods in the lab include: electrophysiology in vitro and in vivo, pharmacology, laser-uncaging, optogenetics, comparative anatomy and immunohistochemistry, in vivo ca-imaging, animal and human psychophysics
Key words: auditory - neuronal circuits - sensory
GSN students
- Current: Barbara Beiderbeck, Matthias Gumbert, Valerija Kello
- Graduated: Dr. Marc Ford, Dr. Kiri Anne Couchman, Dr. Amory H. Danek (née Faber), Dr. Benjamin Haßfurth, Dr. Philipp Rautenberg, Dr. Magdalena Schlesiger, Dr. Veronika Bednarova, Dr. Michael Schutte, Dr. Lara Alisha Nabel, Dr. Diana Amaro Lopes
Selected publications:
1. Beiderbeck B, Müller N, Myoga MH, Friauf F*, Grothe B*, Pecka M* (2018) Precise inhibition in the auditory brainstem fine‐tunes and facilitates action potential firing. Nature Commun 9:1771 https://doi.org/10.1038/s41467-018-04210-y
2. Ford, MC, Alexandrova O, Cossell L, Stange-Marten A, Sinclair J, Kopp-Scheinpflug C, Pecka M, Attwell D, Grothe B (2015) Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing. Nature Communic 25;6:8073 https://doi.org/10.1038/ncomms9073
3. Stange A, Myoga MH, Lingner A, Ford MC, Alexandrowa O, Felmy F, Pecka M, Siveke I, Grothe B (2013) Adaptation in sound localization: from GABAB receptor-mediated synaptic modulation to perception. Nature Neurosci 16:1840-1847 https://doi.org/10.1038/nn.3548
4. Brand A, Behrend O, Marquardt T, McAlpine D, Grothe B (2002) Precise inhibition is essential for microsecond interaural time difference coding. Nature 417: 543-547 https://doi.org/10.1038/417543a
5. Kapfer C, Seidl AH, Schweizer H, Grothe B (2002) Experience-dependent refinement of inhibitory inputs to auditory coincidence-detector neurons. Nature Neurosci 5: 247-253 https://doi.org/10.1038/nn810