Prof. Dr. med. Marco Düring

Primary research focus: Biomedical Neuroscience

Second research focus: Behavioral & Cognitive Neuroscience

Key words: stroke, dementia, MRI, cognition

Brief research description:
We are interested in the mechanisms by which vascular dysfunction causes cognitive decline. The major focus of our work is cerebral small vessel disease, the most common cause of vascular cognitive impairment and also a frequent finding in patients with neurodegenerative disease including Alzheimer’s disease. Our methodological expertise is in structural and functional neuroimaging in humans, using advanced image analysis and statistical techniques.

GSN Students:

Current: Anna Dewenter

Graduated: Dr. Ebru Baykara, Dr. Sofia Finsterwalder

Selected publications:

Dewenter et al., Disentangling the effects of Alzheimer’s and small vessel disease on white matter fibre tracts, Brain 2022, DOI: 10.1093/brain/awac265

Konieczny M & Dewenter A et al., Multi-shell Diffusion MRI Models for White Matter Characterization in Cerebral Small Vessel Disease. Neurology 2021, DOI: 10.1212/WNL.0000000000011213

Finsterwalder S et al., Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimers Dement 2020, DOI: 10.1002/alz.12150

Ter Telgte A et al., The contribution of acute infarcts to cerebral small vessel disease progression. Annals of Neurology 2019, DOI: 10.1002/ana.25556

Baykara E et al., A novel imaging marker for small vessel disease based on skeletonization of white matter tracts and diffusion histograms. Annals of Neurology 2016 DOI: 10.1002/ana.24758 2.