Graduate School of Systemic Neurosciences GSN-LMU
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Nadine Lehnen

Prof. Dr. med. Nadine Lehnen

GSN associate faculty

Responsibilities

Research Group Leader

Contact

TUM Klinikum r. d. Isar
Department of Psychosomatic Medicine
Langerstr. 3
D-81675 München

Phone: +49 89 4140 4313

Further Information

Research focus: We are interested in the mechanisms underlying functional symptoms, i.e. bodily complaints that greatly impact functioning, and quality of life, but are insufficiently explained by organic disease. Using combined computational-experimental approaches we recently could, for the first time, provide evidence for the notion that dysfunctions in the CNS interaction between sensory input and expectations about the sensory consequences of one’s own actions play a role in the emergence and manifestation of these symptoms.

Keywords: Neurobiology of psychosomatic disease / computational and translational psychosomatics, sensorimotor gaze control, vestibular system

GSN Students: Lena Schröder, Dina von Werder

Selected publications:

Schröder L., Regnath F., Glasauer S., Hackenberg A., Hente J., Weilenmann S., Pohl D., von Känel R., Lehnen N. (2022). Altered sensorimotor processing in irritable bowel syndrome: Evidence for a transdiagnostic pathomechanism in functional somatic disorders Front Neurosci. 2022; 16: 1029126.

von Werder, D., Glasauer, S., Schröder, L., Regnath, F., Biersack, K., Van den Bergh, O., & Lehnen, N. (2022, February 15). Post-COVID symptoms in the absence of organic deficit - Lessons from diseases we know. https://doi.org/10.31234/osf.io/yqar2

Associations of Post-Acute COVID syndrome with physiological and clinical measures 10 months after hospitalization in patients of the first wave. Staudt A., Jörres R.A., Hinterberger T., Lehnen N., Loew T., Budweiser S. (2022). Eur J Intern Med. 95: 50–60.

Schröder, L., von Werder, D., Ramaioli, C., Wachtler, T., Henningsen, P., Glasauer, S., & Lehnen, N. (2021). Unstable Gaze in Functional Dizziness: A Contribution to Understanding the Pathophysiology of Functional Disorders. Frontiers in neuroscience, 15, 685590.

Lehnen, N., Radziej, K., Weigel, A., von Känel, R., Glasauer, S., Pitron, V., Van den Bergh, O., Löwe, B., Lehmann, M., Henningsen, P. on behalf of the EURONET-SOMA Group (2020). Complementing conceptual models of persistent somatic symptoms with mathematical formalization. Psychosomatic Medicine, 82(5):527-528.

Lehnen, N., Schröder, L., Glasauer, S., Henningsen, P., & Ramaioli, C. (2019). Deficient head motor control in functional dizziness: Experimental evidence of central sensory-motor dysfunction in persistent physical symptoms. Progress in Brain Research, 249, 385-400.

Van den Bergh, O., & Lehnen, N. (2019). Embracing computational approaches can stimulate clinical psychology research. Clinical Psychology in Europe, 1(3), e39237.

Lehnen, N., Henningsen, P., Ramaioli, C., & Glasauer, S. (2018). An experimental litmus test of the emerging hypothesis that persistent physical symptoms can be explained as perceptual dysregulation. Journal of Psychosomatic Research, 114, 15-17.