Research Group Leader "Translational Neurotechnology"
Klinik für Neurochirurgie
Labor für Translationale Neurotechnologie
Ismaninger Str. 22
Research focus: Cellular mechanisms of higher cognitive functions, cortico-subcortical interactions during goal-directed behavior, neuromodulation of cognition by dopamine
Key words: Controlled behavioral tasks, large-scale extracellular recordings in rodent models and human subjects, optogenetic manipulation of defined cell types and networks, neuroimaging and computational analysis
Jacob SN, Hähnke D and Nieder A. (2018) Structuring of abstract working memory content by fronto-parietal synchrony in primate cortex. Neuron, 99(3):588-597.
Jacob SN, Stalter M and Nieder A. (2016) Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex. Nat Commun, doi: 10.1038/ncomms13218.
Ranganath A and Jacob SN. (2016) Doping the mind: dopaminergic regulation of prefrontal cortical cognition. Neuroscientist, 22(6):593-603.
Ott T, Jacob SN, and Nieder A. (2014) Dopamine receptors differentially enhance rule coding in primate prefrontal cortex neurons. Neuron, 84(6):1317-28.
Jacob SN and Nieder A. (2014) Complementary roles for primate frontal and parietal cortex in guarding working memory from distractor stimuli. Neuron, 83(1):226-37.
Jacob SN, Ott T and Nieder A. (2013) Dopamine regulates two classes of primate prefrontal neurons that represent sensory signals. J Neurosci, 33:13724-34.