Responsibilities
Research Group Leader
Contact
German Center for Vertigo and Balance Disorders
Email:
max.wuehr@med.uni-muenchen.de
Website:
https://www.lmu-klinikum.de/schwindelzentrum/forschung-und-wissenschaft/nachwuchsforschergruppen/dynamische-stand-und-gangkontrolle/c9b7c9605d208cab
Further Information
Keywords: gait & balance disorders, vestibular disorders, sensorimotor control, translational research, non-invasive brain stimulation, deep learning, computer-aided diagnosisResearch methods: Neurophysiological methods: gait analysis, posturography, video-oculography, off-laboratory mobility analysis, EEG; sensory stimulation methods: galvanic vestibular stimulation, 3D-motion platform, VR-setups; AI-/deep-learning methods: pose estimation, clinical decision support systems (CDSS), computer-aided diagnosis (CADx)
Brief research description: My lab is interested in the integration of new sensing technology with applied artificial intelligence to facilitate a computer-aided diagnosis and disease monitoring of common gait disorders and a personalized fall risk prediction. We also work on the development of a wearable non-invasive vestibular prosthesis to augment sensorimotor function in health and treat balance impairments in patients with chronic sensory dysfunction. Moreover, we conduct neurophysiological examinations of healthy and pathological balance regulation with the aim of establishing new biomarkers for the monitoring of intervention effects as well as disease progression.
Selected publications:
Schniepp R, Huppert A, Decker J, Schenkel F, Schlick C, Rasoul A, Dieterich M, Brandt T, Jahn K, Wuehr M. Fall prediction in neurological gait disorders: differential contributions from clinical assessment, gait analysis, and daily-life mobility monitoring. J Neurol. 2021 Sep;268(9):3421-3434. doi: 10.1007/s00415-021-10504-x
Dietrich H, Heidger F, Schniepp R, MacNeilage PR, Glasauer S, Wuehr M. Head motion predictability explains activity-dependent suppression of vestibular balance control. Sci Rep. 2020 Jan 20;10(1):668. doi: 10.1038/s41598-019-57400-z
Wuehr M, Boerner JC, Pradhan C, Decker J, Jahn K, Brandt T, Schniepp R. Stochastic resonance in the human vestibular system - Noise-induced facilitation of vestibulospinal reflexes. Brain Stimul. 2018 Mar-Apr;11(2):261-263. doi: 10.1016/j.brs.2017.10.016
Wuehr M, Brandt T, Schniepp R. Distracting attention in phobic postural vertigo normalizes leg muscle activity and balance. Neurology. 2017 Jan 17;88(3):284-288. doi: 10.1212/WNL.0000000000003516
Wuehr M, Nusser E, Decker J, Krafczyk S, Straube A, Brandt T, Jahn K, Schniepp R. Noisy vestibular stimulation improves dynamic walking stability in bilateral vestibulopathy. Neurology. 2016 Jun 7;86(23):2196-202. doi: 10.1212/WNL.0000000000002748